Brain&Body Centre Logo Logo

release 1
Morphogenetic Model 2D
home  download  screenshots  wiki  forum  contact 

The morphogenetic model is based on the structure of the cortex as a closed surface with glial and axonal fibres pulling radially, the fundamental mechanical properties of cortex and fibres (elasticity and plasticity), and the growth of the cortical surface. The application illustrated several aspects of folding development, such as the relationship between cortical surface and brain volume, the compensation in the degree of folding and the dependence of the degree of folding on cortical thickness. It also shows the effect on folding of early cortical regionalisation and global brain geometry.

Toro R and Burnod Y (2005) A Morphogenetic Model for the Development of Cortical Convolutions. Cerebral Cortex [Link]
Toro R (2012) On the possible shapes of the brain. Evol Biol

last update 20 october 2012, roberto toro
génétique humaine et fonctions cognitives | institut pasteur | paris, FR